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The Consolidation Timeline: 2000-2019 The mergers that created the current oligopoly followed a two-phase pattern
It is becoming a metabolic disease platform where obesity, glycemic control, cardiovascular risk, kidney protection, liver fat reduction, sleep apnea and long-term adherence are increasingly linked
Brand-name GLP-1 medications comprised 68% of the current use compared with 19% for compounded or custom-mixed versions
We also provide an assessment of body weight loss and nausea induced by semaglutide and tirzeapatide across patients with obesity and T2D in the STEP 2 and SURPASS 2 trials compared to those with obesity but not T2D in the STEP 1 and SURMOUNT 1 trials ( Figure 2 )
An analysis of US claims data has indicated that GLP-1 RAs are budget-neutral compared with SoC in people with T2D with a pre-existing CV event
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